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Generic Acalabrutinib

Acalabrutinib is an orally available inhibitor of Bruton’s tyrosine kinase (BTK) with potential antineoplastic activity. Upon administration, acalabrutinib inhibits the activity of BTK and prevents the activation of the B-cell antigen receptor (BCR) signaling pathway. This prevents both B-cell activation and BTK-mediated activation of downstream survival pathways. This leads to an inhibition of the growth of malignant B cells that overexpress BTK. BTK, a member of the src-related BTK/Tec family of cytoplasmic tyrosine kinases, is overexpressed in B-cell malignancies; it plays an important role in B lymphocyte development, activation, signaling, proliferation and survival.

Acalabrutinib is used to treat B cell malignancies (a type of non-Hodgkin lymphoma) including:

  • Mantle cell lymphoma
  • Chronic lymphocytic leukemia

Acalabrutinib sold as brand names Calquence among others.Acalabrutinib has a generic form of several brands include:

  1. LUCIUS Pharma(Suspected illegal manufacturer):LUCIACALABRU(India) 

Acalanib Acalabrutinib

Brand Name : Acalanib
Composition : Acalabrutinib 100mg
Indication: Antineoplastic-BTK inhibitors
Form : Capsule (Oral administration)
Packing : 60 Capsules in 1 box
Manufactured By:DRUG INTERNATIONAL Ltd[Bangladesh]
Storage:Store at room temperature (5-30°C)

PHOACA Acalabrutinib

Brand Name : PHOACA
Composition : Acalabrutinib 100mg
Indication: Antineoplastic-BTK inhibitors
Form : Capsule (Oral administration)
Packing : 60 Capsules in 1 box
Manufactured By:PHARMA 2 VIENTIANE [LAO]
Storage:Store at room temperature (5-30°C)

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