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Generic Ado-Trastuzumab Emtansine

Ado-trastuzumab emtansine(chemical name: T-DM1)is a combination of trastuzumab and the chemotherapy medicine emtansine,Doctors call Kadcyla an ADC(antibody-drug conjugate)targeted therapy.

This medication is used to treat tumors that produce more than the normal amount of a certain substance called HER2 protein.

  • HER2-positive metastatic breast cancer that has previously been treated with Herceptin (chemical name: trastuzumab) and taxane chemotherapy
  • early-stage HER2-positive breast cancer after surgery if residual disease was found after neoadjuvant (before surgery) treatment with Herceptin and taxane chemotherapy

Ado-trastuzumab emtansine sold as brand names Kadcyla ,and It has a generic form of several brands.

Ujvira T-DM 1

Brand Name : Ujvira
Composition : Ado-Trastuzumab Emtansine
Indication:Antineoplastic-Antibody-Drug Conjugates (ADCs) · Antineoplastic-HER2 Targeted Antibody-Microtubule Inhibitor Conjugate
Form : injection(lyophilized powder for reconstitution)
Packing 1: 100mg/vial in 1 bottle
Packing 2: 160mg/vial in 1 bottle
Manufactured By:Zydus Ingenia[India]
Storage : Unused vials: Refrigerate at 2-8ºC (36-46°F)
Reconstituted vials or diluted solutions : Refrigerate at 2-8ºC (36-46°F)/Discard after 24 hr/Do NOT freeze

11 anticancer drugs for treatment HER2+ breast cancer


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