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Generic Avatrombopag

Avatrombopag is an orally available platelet thrombopoietin receptor (TPOR; MPL) agonist, with potential megakaryopoiesis stimulating activity. Upon administration, avatrombopag binds to and stimulates TPOR, which may lead to the proliferation and differentiation of megakaryocytes from bone marrow progenitor cells. This increases the production of platelets and may prevent chemotherapy-induced thrombocytopenia (CIT). TPOR is a cytokine receptor and member of the hematopoietin receptor superfamily.

Avatrombopag is used to treat :

  • Thrombocytopenia (a lack of platelets in the blood) in adults with chronic liver disease who are scheduled to undergo a medical procedure
  • Chronic immune thrombocytopenia (when other treatments have failed)

Avatrombopag sold as brand names Doptelet among others.It has a generic form of several brands include:

  1. DRUG INTERNATIONAL Ltd:Avalet-20(Bangladesh)

 

Avalet Avatrombopag

Brand Name : Avalet-20
Composition : Avatrombopag 20mg
Indication: Antineoplastic-Thrombopoietin Receptor
Form : Tablet (Oral administration)
Packing : 28 Tablets in 1 box
Manufactured By:DIL [Bangla ]
Storage:Store at room temperature (5-30°C)

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