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Generic Baricitinib

Baricitinib is an orally bioavailable inhibitor of Janus kinases 1 and 2 (JAK1/2), with potential anti-inflammatory, immunomodulating and antineoplastic activities. Upon administration, baricitinib binds to JAK1/2, which inhibits JAK1/2 activation and leads to the inhibition of the JAK-signal transducers and activators of transcription (STAT) signaling pathway. This decreases the production of inflammatory cytokines and may prevent an inflammatory response. In addition, baricitinib may induce apoptosis and reduce proliferation of JAK1/2-expressing tumor cells. JAK kinases are intracellular enzymes involved in cytokine signaling, inflammation, immune function and hematopoiesis; they are also upregulated and/or mutated in various tumor cell types.

Baricitinib is used to treat:

  • rheumatoid arthritis
  • In late 2020 was given emergency use authorization as therapy in combination with remdesivir for severe COVID-19

Baricitinib sold as brand names Olumiant among others.Baricitinib has a generic form of several brands include:

  1. Delta Pharma:Baricit(Bangladesh)
  2. Square Pharma:Baritor(Bangladesh)

 

Baricent 2

Brand Name : Baricent
Composition : Baricitinib 2mg
Indication: DMARD – Janus Kinase (JAK) Inhibitors
Form : Tablet (Oral administration)
Packing : 20 Tablet s in 1 box
Manufactured By:Incepta Pharma [Bangladesh]
Storage:Store at room temperature (5-30°C)

Baricinix 2

Brand Name : Baricent
Composition : Baricitinib 2mg
Indication: DMARD – Janus Kinase (JAK) Inhibitors
Form : Tablet (Oral administration)
Packing : 30 Tablet s in 1 box
Manufactured By:Beacon Pharma [Bangladesh]
Storage:Store at room temperature (5-30°C)

Barinat 4

Brand Name : Barinat
Composition : Baricitinib 4mg
Indication: DMARD – Janus Kinase (JAK) Inhibitors
Form : Tablet (Oral administration)
Packing : 14 Tablet s in 1 box
Manufactured By:Natco Pharma [India]
Storage:Store at room temperature (5-30°C)

Palutini 4

Brand Name : Palutini
Composition : Baricitinib 4mg
Indication: DMARD – Janus Kinase (JAK) Inhibitors
Form : Tablet (Oral administration)
Packing : 60Tablet s in 1 box
Manufactured By:TLPH [Laos]
Storage:Store at room temperature (5-30°C)

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