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Generic Cabozantinib

Cabozantinib is an orally bioavailable, small molecule receptor tyrosine kinase (RTK) inhibitor with potential antineoplastic activity. Cabozantinib strongly binds to and inhibits several RTKs, which are often overexpressed in a variety of cancer cell types, including hepatocyte growth factor receptor (MET), RET (rearranged during transfection), vascular endothelial growth factor receptor types 1 (VEGFR-1), 2 (VEGFR-2), and 3 (VEGFR-3), mast/stem cell growth factor (KIT), FMS-like tyrosine kinase 3 (FLT-3), TIE-2 (TEK tyrosine kinase, endothelial), tropomyosin-related kinase B (TRKB) and AXL. This may result in an inhibition of both tumor growth and angiogenesis, and eventually lead to tumor regression.

Cabozantinib is  used to treat:

  • Advanced kidney cancer, sometimes in combination with another medicine called Nivolumab
  • Liver cancer(Renal cell carcinoma,RCC)in people who have been previously treated with Sorafenib
  • Thyroid cancer

Cabozantinib sold as brand name Cometriq、Cabometyx among other.It has a generic form of several brands include:

  1. Julphar Pharma:Cazar(Bangladesh)
  2. Everest Pharma:Caboxen(Bangladesh)
  3. LUCIUS Pharma(Suspected illegal manufacturer):LUCICABOZ(India)
  4. Caprane Pharma(Suspected illegal manufacturer):CABOTINIB(India)
  5. INDAR Pharma(Suspected illegal manufacturer):Cabozandr(India)
  6. Terui Pharmacy(Suspected illegal manufacturer):CABOZTHERUI(India)
  7. Mongla Weiyang(Suspected illegal manufacturer):COBOTINI(Myanmar)
  8. Pharmaxel(Suspected illegal manufacturer):Cabonib(Bangladesh)
  9. Lafepe Pharma(Suspected illegal manufacturer):Cabotin(Paraguay)
  10. SaiLin Bio(Suspected illegal manufacturer):Cabometyx(Laos)

 

Cabocare Cabozantinib

Brand Name : Cabocare
Composition : Cabozantinib 20mg&80mg
Indication: Antineoplastic-Small molecule receptor TKI
Form : Capsule (Oral administration)
Packing : 30 Capsules in 1 box
Manufactured By:Elemento Pharma [Laos]
Storage:Store at room temperature (5-30°C)

Cabonni Cabozantinib

Brand Name : Cabonni
Composition : Cabozantinib 20mg&80mg
Indication: Antineoplastic-Small molecule receptor TKI
Form : Capsule (Oral administration)
Packing :20mg*90Capsules&80mg*30Capsules
Manufactured By:TLPH [Laos]
Storage:Store at room temperature (5-30°C)

Cabanib Cabozantinib

Brand Name : Cabanib
Composition : Cabozantinib 20mg&60mg
Indication: Antineoplastic-Small molecule receptor TKI
Form : Capsule&Tablet (Oral administration)
Packing : 20mg*90Capsules&60mg*30Tablets
Manufactured By:DRUG INTERNATIONAL Ltd[Bangladesh]
Storage:Store at room temperature (5-30°C)

Cabozanix Cabozantinib

Brand Name : Cabozanix
Composition : Cabozantinib 20mg&60mg&80mg
Indication: Antineoplastic-Small molecule receptor TKI
Form : Capsule&Tablet (Oral administration)
Packing : 20mg*90CAP&60mg*30TAB&80mg*30CAP
Manufactured By:Beacon Pharma [Bangladesh]
Storage:Store at room temperature (5-30°C)

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