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Generic Ceritinib

Ceritinib is an oral ATP-competitive ALK and ROS1 TKI, but contrary to crizotinib does not have MET TKI activity, nevertheless may inhibit other receptors to a lesser extent such as the insulin-like growth factor 1 receptor (IGF-1) .

In vitro, ceritinib inhibits ALK with a 20-fold greater potency than crizotinib, crosses the blood-brain barrier (BBB) in vivo and shows nanomolar potency against patient-derived crizotinib-resistant tumor cell lines.

Ceritinib is approved for the treatment of metastatic ALK mutated NSCLC in patients who are unable to tolerate or have progressed on prior crizotinib therapy.

Ceritinib sold as brand name Zykadia、Spexib.It has a generic form of several brands include:

  1. Genvio Pharma:Erinlar(Bangladesh)
  2. LUCIUS Pharma(Suspected illegal manufacturer):LUCICER(India)

Spexib Ceritinib

Brand Name : Spexib [Developing countries Brand Name]
Composition : Ceritinib 150mg
Indication: Antineoplastic-Anaplastic Lymphoma Kinase (ALK) Inhibitor
Form : Capsule (Oral administration)
Packing : 150 Capsules in 1 box
Manufactured By:Novartis [ India and Vietnam]
Storage:Store at room temperature (5-30°C)

NOXALK Ceritinib

Brand Name : NOXALK
Composition : Ceritinib 150mg
Indication: Antineoplasic- Anaplastic Lymphoma Kinase (ALK) Inhibitor
Form : Capsule (Oral)
Packing : 90 Capsules in 1 box
Manufactured By:Natco Pharma [India]
Storage:Store at room temperature (5-30°C)

Cerinib Ceritinib

Brand Name : Cerinib
Composition : Ceritinib 150mg
Indication: Antineoplastic- Anaplastic Lymphoma Kinase (ALK) Inhibitor
Form : Capsule (Oral administration)
Packing : 30 Capsules in 1 box
Manufactured By:DRUG INTERNATIONAL Ltd[Bangladesh]
Storage:Store at room temperature (5-30°C)

Cerini Ceritinib

Brand Name : Cerini
Composition : Ceritinib 150mg
Indication: Antineoplastic-Anaplastic Lymphoma Kinase (ALK) Inhibitor
Form : Capsule (Oral administration)
Packing : 50 Capsule s in 1 box
Manufactured By:TLPH [Laos]
Storage:Store at room temperature (5-30°C)

6 Targeted drugs for treatment ALK lung cancer

4 Targeted drugs for treatment ROS1+ lung cancer

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