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Generic Gilteritinib

Gilteritinib is an orally bioavailable inhibitor of the receptor tyrosine kinases (RTKs) FMS-related tyrosine kinase 3 (FLT3, STK1, or FLK2), AXL (UFO or JTK11) and anaplastic lymphoma kinase (ALK or CD246), with potential antineoplastic activity. Gilteritinib binds to and inhibits both the wild-type and mutated forms of FLT3, AXL and ALK. This may result in an inhibition of FLT3, AXL, and ALK-mediated signal transduction pathways and reduces tumor cell proliferation in cancer cell types that overexpress these RTKs. FLT3, AXL and ALK, overexpressed or mutated in a variety of cancer cell types, play a key role in tumor cell growth and survival.

Gilteritinib is used to treat:

  • Acute myeloid leukemia with FLT3 mutations(AML)

Bosutinib sold as brand name  Xospata among other.It has a generic form of several brands include:

GITELI Gilteritinib

Brand Name : GITELI
Composition : Gilteritinib 40mg
Indication: Antineoplastic-FLT3 TKI
Form : Tablet (Oral administration)
Packing : 90 Tablets in 1 box
Manufactured By:Louang Namtha Pharma [Laos]
Storage:Store at room temperature (5-30°C)

Giltedx Gilteritinib

Brand Name : Giltedx
Composition : Gilteritinib 40mg
Indication: Antineoplastic-FLT3 TKI
Form : Tablet (Oral administration)
Packing : 84 Tablets in 1 box
Manufactured By:DAXIONG Pharma [Laos]
Storage:Store at room temperature (5-30°C)

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