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Generic Miglustat

Miglustat is a synthetic, N-alkylated imino analogue of D-glucose. Miglustat competitively and reversibly binds to and inhibits the activity of UDP-glucose ceramide glucosyltransferase, which catalyzes the initial step in the synthesis of glycosphingolipids (GSL). This leads to a decrease in the production of glycosphingolipid, which has important roles in various cellular processes. Miglustat can be used in substrate reduction therapy in diseases in which the enzyme glucocerebrosidase, that is responsible for the breakdown of GSL, is deficient.

Miglustat is used to treat :

  • Type 1 Gaucher’s Disease
  • Type C Niemann–Pick Disease

Miglustat sold as brand names Zavesca among others.Miglustat has a generic form of several brands include:

  1. GEROT LANNACH-MIGLUSTAT GL PHARMA(Austria)
  2. Piramal critical care:Yargesa(UK)
  3. Dipharma-MIGLUSTAT Dipharma(Switzerland)
  4. Bluefish Pharma-Miglustat Bluefish(Sweden)

 

Miglustat Accord

Brand Name : Miglustat Accord
Composition : Miglustat 100mg
Indication: Metabolic Modifier
Form : Capsule (Oral administration)
Packing : 84 Capsules in 1 box
Manufactured By: Accord Healthcare [Germany]
Storage:Store at room temperature (5-30°C)

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