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Generic Osimertinib

Osimertinib(Name used before AZD9291) is a third-generation, orally available, irreversible, mutant-selective, epidermal growth factor receptor (EGFR) inhibitor, with potential antineoplastic activity. Upon oral administration, osimertinib covalently binds to and inhibits the activity of mutant forms of EGFR, including the T790M EGFR mutant, thereby preventing EGFR-mediated signaling.This may both induce cell death and inhibit tumor growth in EGFR-overexpressing tumor cells. EGFR, a receptor tyrosine kinase mutated in many tumor cell types, plays a key role in tumor cell proliferation and tumor vascularization.

AZD9291 preferentially inhibits mutated forms of EGFR including T790M, a secondarily-acquired resistance mutation, and may have enhanced anti-tumor effects in tumors with T790M-mediated resistance when compared to other EGFR tyrosine kinase inhibitors. As this agent is selective towards mutant forms of EGFR, its toxicity profile may be reduced when compared to non-selective EGFR inhibitors which also inhibit wild-type EGFR.

Osimertinib sold as brand name Tagrisso.It has a generic form of several brands include:

  1. Julphar Pharma:TASSO(Bangladesh)
  2. Genvio Pharma:Irmukin(Bangladesh)
  3. Techno Drugs Ltd:Tagribo(Bangladesh)
  4. Tuteur Pharma:OSITERIB(Argentina)
  5. LUCIUS Pharma(Suspected illegal manufacturer):LUCIOSIM (India)
  6. Healthkind Labs(Suspected illegal manufacturer):Osicon(India)
  7. Caprane Pharma(Suspected illegal manufacturer):OSIM(India)
  8. KASO Pharma(Suspected illegal manufacturer):OSIKASO(India)
  9. INDAR Pharma(Suspected illegal manufacturer):Osiinda(India)
  10. AYUS Pharma(Suspected illegal manufacturer):Ayusomier(India)
  11. ACPI Pharma(Suspected illegal manufacturer):Tagribay(India)
  12. Numarks Pharma(Suspected illegal manufacturer):OsimertiG80(Nepal)
  13. Mongla Weiyang(Suspected illegal manufacturer):OSITINE(Myanmar)
  14. Pharmaxel Pharma(Suspected illegal manufacturer):Osimib(Bangladesh)
  15. Techno Pharma(Suspected illegal manufacturer):Tagribo(Bangladesh)
  16. Asso Pharma(Suspected illegal manufacturer):Tagasso(Bangladesh)
  17. Julphar Pharma(Suspected illegal manufacturer):Osiwam(Bangladesh)
  18. Libbs Pharma(Suspected illegal manufacturer):Tagriasso(Brazil)
  19. Lafepe Pharma(Suspected illegal manufacturer):OSMERTIN(Paraguay)
  20. KNP PHARMA Sole(Suspected illegal manufacturer):Osimerterui(Laos)
  21. SaiLin Pharma(Suspected illegal manufacturer):Tagrisso(Laos)

Tagrix Osimertinib

Brand Name : Tagrix
Composition : Osimertinib 80mg
Indication: Antineoplastic-3rd generation EGFR tyrosine kinase inhibitor
Form : Tablet (Oral administration)
Packing : 30 Tablets in 1 box
Manufactured By:Beacon Pharma [Bangladesh]
Storage:Store at room temperature (5-30°C)

Osicent Osimertinib

Brand Name : Osicent
Composition : Osimertinib 80mg
Indication: Antineoplastic-3rd generation EGFR tyrosine kinase inhibitor
Form : Tablet (Oral administration)
Packing : 30 Tablets in 1 box
Manufactured By:Incepta Pharma [Bangladesh]
Storage:Store at room temperature (5-30°C)

Osimert Osimertinib

Brand Name : Osimert
Composition : Osimertinib 80mg
Indication: Antineoplastic-3rd generation EGFR tyrosine kinase inhibitor
Form : Tablet (Oral administration)
Packing : 30 Tablets in 1 box
Manufactured By:Everest Pharma [Bangladesh]
Storage:Store at room temperature (5-30°C)

Osinib Osimertinib

Brand Name : Osinib
Composition : Osimertinib 80mg
Indication: Antineoplastic-3rd generation EGFR tyrosine kinase inhibitor
Form : Tablet (Oral administration)
Packing : 30 Tablets in 1 box
Manufactured By:DRUG INTERNATIONAL Ltd[Bangladesh]
Storage:Store at room temperature (5-30°C)

Osiem Osimertinib

Brand Name : Osiem
Composition : Osimertinib 80mg
Indication: Antineoplastic-3rd generation EGFR tyrosine kinase inhibitor
Form : Tablet (Oral administration)
Packing : 30 Tablets in 1 box
Manufactured By:TLPH [Laos]
Storage:Store at room temperature (5-30°C)

PHO SIMER Osimertinib

Brand Name : PHO SIMER
Composition : Osimertinib 80mg
Indication: Antineoplastic-3rd generation EGFR tyrosine kinase inhibitor
Form : Tablet (Oral administration)
Packing : 30 Tablets in 1 box
Manufactured By:PHARMA 2 VIENTIANE [Laos]
Storage:Store at room temperature (5-30°C)

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