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Generic Temozolomide

Temozolomide is a triazene analog of dacarbazine with antineoplastic activity. As a cytotoxic alkylating agent, temozolomide is converted at physiologic pH to the short-lived active compound, monomethyl triazeno imidazole carboxamide (MTIC). The cytotoxicity of MTIC is due primarily to methylation of DNA at the O6 and N7 positions of guanine, resulting in inhibition of DNA replication. Unlike dacarbazine, which is metabolized to MITC only in the liver, temozolomide is metabolized to MITC at all sites. Temozolomide is administered orally and penetrates well into the central nervous system.

Temozolomide is used to treat:

  • Glioblastoma Multiforme
  • Anaplastic Astrocytoma

Temozolomide sold as brand name Temodal among other.It has a generic form of several brands include:

  1. Dr Reddy’s Lab:Glioz(India)
  2. Zydus Cadila:Nublast(India)
  3. Celon Lab:Temolon(India)
  4. Hetero Drugs:Temotero(India)
  5. Panacea Biotec:Temotrust(India)
  6. Sun Pharmaceutical Industries Ltd:Gliotem(India)
  7. Alkem Lab:Glistroma(India)
  8. Khandelwal Lab:Temozol(India)
  9. Flagship Biotech:CEREZOL(India)
  10. Medicare Remedies:TEMZOCARE(India)
  11. Oncozest:Gliogery(India)
  12. Getwell:Temzol(India)
  13. Verve Biosciences:Temospan
  14. MEDILIFE:MOZOTIZE
  15. Reliance:TemoRel
  16. AURCATC:GBMT
  17. Jenome Biophar:Benzimide(India)
  18. Emcure:Temcure(India)
  19. AaltraMed:TEMONIDE(India)
  20. Admac Lifesciences:Benzomide(India)
  21. CMG:TEMOZIDE(India)
  22. GLS Pharma:Temoget(India)
  23. RPG Life Sciences Ltd:TEMOTIDE(India)
  24. NEON:TABZE(India)
  25. Taj Pharma-Temozolomide(India)
  26. FACMED PHARMA-Temozolomide(India)
  27. Beacon Pharma:Temonix(Bangladesh)
  28. Drug International Ltd:Temozar(Bangladesh)
  29. Techno Drugs Ltd:Zolomide(Bangladesh)
  30. Accord HC-Temozolomide Accord(EU)
  31. Areva Pharma-Temozolomide(US)
  32. Varifarma:VARIZOLOMIDA (Argentina)

Temoside 20

Brand Name:Temoside 20
Composition:Temozolomide 20mg
Indication: Antineoplastic-Alkylating Agent-Triazenes
Form : Capsule(Oral administration)
Packing : 5 Capsules in 1 box
Manufactured By:Cipla Ltd [India]
Storage:Store at room temperature (5-30°C)

Temoside 100

Brand Name:Temoside 100
Composition:Temozolomide 100mg
Indication: Antineoplastic-Alkylating Agent-Triazenes
Form : Capsule(Oral administration)
Packing : 5 Capsules in 1 box
Manufactured By:Cipla Ltd [India]
Storage:Store at room temperature (5-30°C)

Temoside 250

Brand Name:Temoside 250
Composition:Temozolomide 100mg
Indication: Antineoplastic-Alkylating Agent-Triazenes
Form : Capsule(Oral administration)
Packing : 5 Capsules in 1 box
Manufactured By:Cipla Ltd [India]
Storage:Store at room temperature (5-30°C)

Temonat Temozolomide

Brand Name: Temonat
Composition:Temozolomide 20mg&100mg&250mg
Indication: Antineoplastic-Alkylating Agent-Triazenes
Form : Capsule(Oral administration)
Packing : 5 Capsules in 1 box
Manufactured By:Natco Pharma [India]
Storage:Store at room temperature (5-30°C)

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