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Tag: Breast Cancer

Generic Tucatinib

Tucatinib is an orally bioavailable inhibitor of the human epidermal growth factor receptor tyrosine kinase ErbB-2 (also called HER2) with potential antineoplastic activity. Tucatinbib is used to treat : with Trastuzumab and capecitabine in the treatment of unresectable or metastatic HER-2 positive breast cancer Tucatinbib sold as brand names Tukysa . . . Read more

Generic Abemaciclib

Abemaciclib is an orally available cyclin-dependent kinase (CDK) inhibitor that targets the CDK4 (cyclin D1) and CDK6 (cyclin D3) cell cycle pathway, with potential antineoplastic activity. Abemaciclib specifically inhibits CDK4 and 6, thereby inhibiting retinoblastoma (Rb) protein phosphorylation in early G1. Inhibition of Rb phosphorylation prevents CDK-mediated G1-S phase transition, . . . Read more

Generic Talazoparib

Talazoparib is the only once-daily oral PARP inhibitor for the treatment of gBRCA-mutated hormone receptor—positive (HR+)/HER2- or triple-negative locally advanced or metastatic breast cancer. Talzenna is a pill taken by mouth. The recommended starting dose of Talzenna is a 1-mg tablet taken once per day, with or without food. Before . . . Read more

Generic Olaparib

Olaparib is a small molecule inhibitor of the nuclear enzyme poly(ADP-ribose) polymerase (PARP) with potential chemosensitizing, radiosensitizing, and antineoplastic activities. Olaparib is approved to treat: Breast cancer that is HER2 negative, has certain germline mutations in the BRCA1 or BRCA2 gene, and has metastasized (spread to other parts of the . . . Read more

Generic Ado-Trastuzumab Emtansine

Ado-trastuzumab emtansine(chemical name: T-DM1)is a combination of trastuzumab and the chemotherapy medicine emtansine,Doctors call Kadcyla an ADC(antibody-drug conjugate)targeted therapy. This medication is used to treat tumors that produce more than the normal amount of a certain substance called HER2 protein. HER2-positive metastatic breast cancer that has previously been treated with Herceptin . . . Read more

Generic Neratinib

Neratinib is a treatment for early stage breast cancer that is HR+(hormone receptor positive) and  HER2+(human epidermal growth factor receptor 2 positive,HER2 positive) 。 Neratinib sold as brand names Nerlynx ,and It has a generic form of several brands include: Lafepe Pharma(Suspected illegal manufacturer):NENATIN Brand Name : Hertinib Composition : Neratinib . . . Read more

Generic Lapatinib

Lapatinib, the first dual inhibitor of epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2) tyrosine kinases. Lapatinib tablets is used: with the medicine capecitabine to treat people with breast cancer that is advanced or that has spread to other parts of the body (metastatic), and: that . . . Read more

Generic Alpelisib

Alpelisib is used in men and postmenopausal women with HR-positive, HER2-negative breast cancer that is advanced or has spread to other parts of the body (metastatic). Alpelisib is used only if your cancer has a specific genetic marker (an abnormal “PIK3CA” gene). Your doctor will test you for this gene. . . . Read more

Generic Ribociclib

Ribociclib  is classified as a CDK 4/6 inhibitor (cyclin-dependent kinase 4/6 inhibitor).IT’s used in combination with: an aromatase inhibitor to treat pre/perimenopausal or postmenopausal women with hormone receptor HR+(HR-positive), human epidermal growth factor receptor 2 HER2-(HER2-negative) breast cancer that has spread to other parts of the body (metastatic), as the . . . Read more

Generic Palbociclib

Palbociclib is used in combination with letrozole (an aromatase inhibitor) to treat postmenopausal women with estrogen receptor ER+(ER-positive) , HER2-(HER2-negative) advanced breast cancer.Palbociclib is a targeted therapy. This medication is classified as a CDK 4/6 inhibitor (cyclin-dependent kinase 4/6 inhibitor). Palbociclib is the generic name for the trade name drug . . . Read more