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Tag: COVID-19

Generic Baricitinib

Baricitinib is an orally bioavailable inhibitor of Janus kinases 1 and 2 (JAK1/2), with potential anti-inflammatory, immunomodulating and antineoplastic activities. Upon administration, baricitinib binds to JAK1/2, which inhibits JAK1/2 activation and leads to the inhibition of the JAK-signal transducers and activators of transcription (STAT) signaling pathway. This decreases the production . . . Read more

Generic Remdesivir

Remdesivir is a prodrug of an adenosine triphosphate (ATP) analog, with potential antiviral activity against a variety of RNA viruses. In the US, remdesivir is approved by the FDA to treat coronavirus infection, also known as COVID-19, for certain patients who are in the hospital. Remdesivir sold as brand names . . . Read more

Generic Favipiravi

Favipiravir(T-705) Discovered by Toyama Chemical Co., Ltd. in Japan, favipiravir is a modified pyrazine analog that was initially approved for therapeutic use in resistant cases of influenza.  Not only does favipiravir inhibit replication of influenza A and B, but the drug has shown promise in the treatment of avian influenza, . . . Read more