Rituximab and Biosimilars
About Rituximab [anti-CD20 antibody]
Rituximab is a chimeric monoclonal antibody against the protein CD20, which is primarily found on the surface of immune system B cells. When it binds to this protein it triggers cell death.
Rituximab used to treat certain autoimmune diseases and types of cancer. It is used for non-Hodgkin lymphoma, chronic lymphocytic leukemia, rheumatoid arthritis, granulomatosis with polyangiitis, idiopathic thrombocytopenic purpura, pemphigus vulgaris, myasthenia gravis and Epstein–Barr virus-positive mucocutaneous ulcers.
Commercial Products
| Attributes | RD code | Brand Name | Approved | Owner | Area | WebSite |
|---|---|---|---|---|---|---|
| Originator | D2E7 | MabThera® /Rituxan® | 1997 | Biogen and Genentech by Roche | USA | roche.com |
| Biosimilar | IBI303 | Halpryza® (CNN：达伯华®) | 2020 | InnoventBio(CNN：信达生物) | China | innoventbio.com |
| Biosimilar | HLX01 | CNN：汉利康® | 2019 | Henlius (CNN：复宏汉霖) | China | henlius.com |
| Biosimilar | TQB2303 | CNN：得利妥® | 2023 | CHIATHAI TIANQIONG(CNN：正大天晴药业) | China | cttq.com |
| Biosimilar | CXSS2200092 | CNN：生利健® | 2024 | SinoPharm(CNN：上海生物) | China | siobp.com |
| Biosimilar | CXSS2400015 | CNN：益立达® | 2025 | LuNanPharm(CNN：山东新时代) | China | lunan.com.cn |
Business Cooperation
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