Mitotane 500mg


Mitotane is used to treat cancer of the adrenal glands (adrenocortical carcinoma) that cannot be removed by surgery.

This medicine acts on a part of the body called the adrenal cortex. Mitotane reduces the amount of steroids (cortisone-like hormones) that are produced by the adrenal cortex.The drug is also sometimes used in the treatment of Cushing’s syndrome.


MITODX (Mitotane) is a steroidogenesis inhibitor and cytostatic antineoplastic medication which is used in the treatment of adrenocortical carcinoma and Cushing’s syndrome.

 MITODX Registration Number: 08L1004/23

Mitotane is an inhibitor of the adrenal cortex. It acts as an inhibitor of cholesterol side-chain cleavage enzyme (P450scc, CYP11A1), and also of 11β-hydroxylase (CYP11B1), 18-hydroxylase (aldosterone synthase, CYP11B2), and 3β-hydroxysteroid dehydrogenase (3β-HSD) to a lesser extent. In addition, mitotane has direct and selective cytotoxic effects on the adrenal cortex, via an unknown mechanism, and thereby induces permanent adrenal atrophy similarly to DDD.

Mitotane comes as a tablet to take by mouth. It is usually taken three to four times a day. Take mitotane at around the same times every day. The pill should be swallowed whole with a glass of water. Do not crush, chew or break. Mitotane should be taken with meals that have fat-rich foods, such as milk, chocolate, and oil..

BigBear Pharmaceutical is one of the regular chemical pharmaceutical companies in Laos.


Life saving meds are either beyond the reach of general people or not available in many countries. Because of the patient exemptions for Lao’s companies,RxLibra Development can supply the patented drugs. As a support to global patient.


Patient Assistance Program

Patient Eligibility: Patient has a valid prescription for Mitotane  

Financial Assistance:  Buy 2 boxes and get 1 box free.

Working Time: Monday through Friday, 10 AM to 6 PM [Indochina time]

MobilePhone/WhatsApp/Line: +856 20 54 177 436

Project Expirated: 18/APR/2024-18/APR/2025